Article

Refining the impact of genetic evidence on clinical success

2023-06-29

Abstract excerpt

The cost of drug discovery and development is driven primarily by failure, with just ∼10% of clinical programs eventually receiving approval. We previously estimated that human genetic evidence doubles the success rate from clinical development to approval. In this study we leverage the growth in genetic evidence over the past decade to better understand the characteristics that distinguish clinical success and fa...

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Literature Corpus work: 3de34bf3-a3b8-533b-a5b0-0b01f99c5abf
DOI: 10.1101/2023.06.23.23291765

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