Article

Transcriptional alteration in TRKβ-SHC isoform as a neuroprotective factor for post stroke memory outcome

2026-02-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Post-stroke cognitive impairment (PSCI) affects nearly 30% of stroke survivors and significantly impairs functional recovery. Brain-derived neurotrophic factor (BDNF)–tropomyosin receptor kinase-β (Trkβ) signalling is crucial for synaptic plasticity and cognitive function. While altered expression of truncated TRKβ-T1 isoforms has been linked to stroke, the contribution of t...

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Literature Corpus work: dbf01931-7806-5e10-a0f6-24d0740109d0
DOI: 10.64898/2026.02.21.26346768

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