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Article

Associations of BDNF genotype and promoter methylation with acute and long-term stroke outcomes in an East Asian cohort.

PloS one - 1 Jan 2012

Kim Jae-Min, Stewart Robert, Park Man-Seok, Kang Hee-Ju, Kim Sung-Wan, Shin Il-Seon, Kim Hye-Ran, Shin Myung-Geun, Cho Ki-Hyun, Yoon Jin-Sang

Abstract excerpt

BACKGROUND: Brain derived neurotrophic factor (BDNF) has been shown to play an important role in poststroke recovery. BDNF secretion is influenced by genetic and epigenetic profiles. This study aimed to investigate whether BDNF val66met polymorphism and promoter methylation status were associated with outcomes at two weeks and one year after stroke. METHODS AND FINDINGS: A total of 286 patients were evaluated at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23240009
DOI: 10.1371/journal.pone.0051280
PMCID: PMC3519835

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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