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Article

Lack of association of TNF-238A and -308A in Japanese patients with psoriasis vulgaris, psoriatic arthritis and generalized pustular psoriasis.

Journal of dermatological science - 1 Sept 2002

Nishibu Akiko, Oyama Noritaka, Nakamura Koichiro, Kaneko Fumio

Abstract excerpt

Tumor necrosis factor (TNF)-alpha is one of the proinflammatory cytokines and immunomodulators, and has an important pathogenetic role in psoriasis. The TNF-alpha gene (TNFA) is in the human leukocyte antigen (HLA) class III locus on chromosome 6, which might be related to the pathogenesis of psoriasis. It has been suggested that some polymorphisms of the TNFA gene promoter, especially G to A conversions at...

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Source

Identifiers

PMID: 12234707
DOI: 10.1016/s0923-1811(02)00022-1

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lack of association of TNF-238A and -308A in Japanese patients with psoriasis vulgaris, psoriatic arthritis and generalized pustular psoriasis.PMID 12234707Read ↗

Lack of association between the promoter polymorphisms at positions -308 and -238 of the tumor necrosis factor alpha gene and psoriasis vulgaris in Japanese patients.Semantic proximity Read ↗

308G/A and 238G/A polymorphisms in the TNF-α gene may not contribute to the risk of arthritis among Turkish psoriatic patientsSemantic proximity Read ↗

TNF-alpha gene promoter -238G>A and -308G>A polymorphisms alter risk of psoriasis vulgaris: a meta-analysis.Semantic proximity Read ↗

A - 308 promoter polymorphism of tumor necrosis factor alpha gene does not associate with the susceptibility to psoriasis vulgaris. No difference either between psoriasis type I and type II patients.Semantic proximity Read ↗

Tumor necrosis factor alpha gene promoter -238G/A polymorphism increases the risk of psoriasis vulgaris in Indian patients.Semantic proximity Read ↗

Polymorphisms in the TNFA promoter region is not associated with palmoplantar pustulosis.Semantic proximity Read ↗

Single nucleotide polymorphisms in the tumor necrosis factor-alpha gene promoter region alter the risk of psoriasis vulgaris and psoriatic arthritis: a meta-analysis.Semantic proximity Read ↗

Association of the tumour necrosis factor-α polymorphisms rs361525 and rs1800629 with susceptibility to psoriasis: a meta-analysis.Semantic proximity Read ↗

Polymorphisms of tumor necrosis factor (TNF) alpha and beta genes in Korean patients with psoriasis.Semantic proximity Read ↗

TNF-α gene -238G>A polymorphism is associated with psoriasis patients.Semantic proximity Read ↗

A Meta-Analysis of the Relationship between Tumor Necrosis Factor-α Polymorphisms and Psoriasis.Semantic proximity Read ↗

Tumor Necrosis Factor-α 308 G/A polymorphism and psoriasis risk: A pooled analysis in different populations.Semantic proximity Read ↗

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