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Article

TNF-α gene -238G>A polymorphism is associated with psoriasis patients.

Journal of cosmetic dermatology - 1 Jun 2022

Akcılar Raziye, Dizen Namdar Nazlı, Yükcü Fulya, Arslan Utku Selve

Abstract excerpt

BACKGROUND: Tumor necrosis factor-alpha (TNF-α) is a protein that plays a key role in the pathophysiology of chronic inflammatory disorders like psoriasis. AIMS: The goal of this study was to see whether the TNF-α gene -238G>A polymorphism was linked to psoriasis susceptibility. METHODS: This study comprised 90 psoriasis patients and ninety healthy controls. For the TNF-α gene -238G>A polymorphism, genomic DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35340111
DOI: 10.1111/jocd.14940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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TNF-α gene -238G>A polymorphism is associated with psoriasis patients.PMID 35340111Read ↗

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A - 308 promoter polymorphism of tumor necrosis factor alpha gene does not associate with the susceptibility to psoriasis vulgaris. No difference either between psoriasis type I and type II patients.Semantic proximity Read ↗

Human leukocyte antigen (HLA) and single nucleotide polymorphisms (SNPs) tumor necrosis factor (TNF)-alpha -238 and -308 as genetic markers of susceptibility to psoriasis and severity of the disease in a long-term follow-up Brazilian study.Semantic proximity Read ↗

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