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Article

TNF-alpha gene promoter -238G>A and -308G>A polymorphisms alter risk of psoriasis vulgaris: a meta-analysis.

The Journal of investigative dermatology - 1 Aug 2007

Li Chunying, Wang Gang, Gao Ying, Liu Ling, Gao Tianwen

Abstract excerpt

Tumor necrosis factor-alpha (TNF-alpha) is a major proinflammatory cytokine and involved in the etiology of psoriasis. The -238G>A and -308G>A polymorphisms influence the transcription of the TNF-alpha gene and have been implicated in psoriasis risk. However, the results from the published studies on the association between TNF-alpha polymorphisms and psoriasis risk are conflicting. Our meta-analysis of a total...

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Identifiers

PMID: 17446901
DOI: 10.1038/sj.jid.5700822

Genes

TNF

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TNF-alpha gene promoter -238G>A and -308G>A polymorphisms alter risk of psoriasis vulgaris: a meta-analysis.PMID 17446901Read ↗

Tumor necrosis factor alpha gene promoter -238G/A polymorphism increases the risk of psoriasis vulgaris in Indian patients.Semantic proximity Read ↗

TNF-α gene -238G>A polymorphism is associated with psoriasis patients.Semantic proximity Read ↗

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Tumor Necrosis Factor-α 308 G/A polymorphism and psoriasis risk: A pooled analysis in different populations.Semantic proximity Read ↗

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TNF-308 G/A polymorphism and risk of acne vulgaris: a meta-analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms in the tumor necrosis factor-alpha gene promoter region alter the risk of psoriasis vulgaris and psoriatic arthritis: a meta-analysis.Semantic proximity Read ↗

A - 308 promoter polymorphism of tumor necrosis factor alpha gene does not associate with the susceptibility to psoriasis vulgaris. No difference either between psoriasis type I and type II patients.Semantic proximity Read ↗

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Associations of promoter region polymorphisms in the tumour necrosis factor-? gene and early-onset psoriasis vulgaris in a northern Polish populationSemantic proximity Read ↗

Different Transcriptional Activity and In Vitro TNF-α Production in Psoriasis Patients Carrying the TNF-α 238A Promoter PolymorphismSemantic proximity Read ↗

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