Article

Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma Pathophysiology

2024-09-20

Abstract excerpt

Gliomas are primary brain tumors that develop from glial cells within the central nervous system and are among the deadliest human cancers. Glioblastoma (GBM) is the most malignant form of glioma. NLRX1 is an innate immune pattern recognition receptor that exhibits tumor-suppressive and tumor-promoting effects that may be cancer or cell-type, context-dependent, aided by differences in the microenvironment. Here, w...

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Literature Corpus work: dbd43f09-3725-5c6e-9b28-2aebe8a68470
DOI: 10.1101/2024.09.19.613932

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