Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Expression Profile of NLRs and AIM2 in Glioma and Implications for NLRP12 in Glioblastoma

11 Jun 2019

Abstract excerpt

Gliomas are the most prevalent primary brain tumors with immense clinical heterogeneity, poor prognosis and survival. The nucleotide-binding domain, and leucine-rich repeat containing receptors (NLRs) and absent-in-melanoma 2 (AIM2) are innate immune receptors crucial for initiation and progression of several cancers. There is a dearth of reports linking NLRs and AIM2 to glioma pathology. NLRs are expressed by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Immune cells in cancer
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31186453
DOI: 10.1038/s41598-019-44854-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Expression Profile of NLRs and AIM2 in Glioma and Implications for NLRP12 in GlioblastomaPMID 31186453Read ↗

Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma PathophysiologySemantic proximity Read ↗

Nucleotide‐Binding Oligomerization Domain (NOD)-Like Receptor Subfamily C (NLRC) as a Prognostic Biomarker for Glioblastoma Multiforme Linked to Tumor Microenvironment: A Bioinformatics, Immunohistochemistry, and Machine Learning-Based StudySemantic proximity Read ↗

Prognostic Neurotransmitter Receptors Genes Are Associated with Immune Response, Inflammation and Cancer Hallmarks in Brain TumorsSemantic proximity Read ↗

Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical DevelopmentsSemantic proximity Read ↗

SIRPB1 regulates inflammatory factor expression in the glioma microenvironment via SYK: functional and bioinformatics insightsSemantic proximity Read ↗

LGALS3 Is a Poor Prognostic Factor in Diffusely Infiltrating Gliomas and Is Closely Correlated With CD163+ Tumor-Associated MacrophagesSemantic proximity Read ↗

Progenitor Cells, Microglia, and Non-coding RNAs: Orchestrators of Glioblastoma Pathogenesis and Therapeutic ResistanceSemantic proximity Read ↗

FDX1 serves as a prognostic biomarker and promotes glioma progression by regulating the immune responseSemantic proximity Read ↗

Expression of TLR9 within human glioblastomaSemantic proximity Read ↗

SorLA restricts TNFα release from microglia to shape glioma-supportive brain microenvironmentSemantic proximity Read ↗

Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1Semantic proximity Read ↗

Exosomal Lnc-DLK1-35 reprograms microglia into a pro-tumorigenic phenotype via a non-canonical cytokine signature to promote glioblastoma progression and chemoresistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.