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Article

Molecular profiles and immunomodulatory activities of glioblastoma-derived exosomes

1 Jan 2020

Abstract excerpt

Abstract Background Glioblastoma is one of the most immunosuppressive human tumors. Emerging data suggest that glioblastoma-derived exosomes (GBex) reprogram the tumor microenvironment into a tumor-promoting milieu by mechanisms that not yet understood. Methods Exosomes were isolated from supernatants of glioblastoma cell lines by size exclusion chromatography. The GBex endosomal origin, size, protein cargos, and...

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Share to Extracellular vesicles in disease
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PMID: 32642708
DOI: 10.1093/noajnl/vdaa056

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