Article

Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma

2023-04-06

Abstract excerpt

Glioblastomas (GBMs) are tumors of the central nervous system that remain recalcitrant to both standard of care chemo-radiation and immunotherapies. Emerging approaches to treat GBMs include depletion or re-education of innate immune cells including microglia (MG) and macrophages (MACs). Here we show myeloid cell restricted expression of triggering receptor expressed on myeloid cells 2 (TREM2) across low- and high...

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Literature Corpus work: 9ea457a5-8bda-524e-99d3-21bb19e4d682
DOI: 10.1101/2023.04.05.535792

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