Article

Identifying memory gene expression from single sample scRNA-seq data using power law signatures

2025-01-16

Abstract excerpt

Genes with expression levels that fluctuate on time scales longer than cell division times are associated with cancer drug tolerance. However, current methods for identifying such ‘memory’ genes rely on variants of the Luria-Delbrück experiment and require either multiple replicates or lineage information, limiting their use to model systems or in-vitro settings. We develop a new conceptual approach using recent...

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Literature Corpus work: dbc3e609-f426-5033-82c1-df5f9c13610e
DOI: 10.1101/2025.01.15.633183

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