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The human cytomegalovirus UL116 glycoprotein is a chaperone to control gH-based complexes levels on virions

2020-11-18

Abstract excerpt

<h4>ABSTRACT</h4> Human cytomegalovirus (HCMV) relies in large part upon the viral membrane fusion glycoprotein B (gB) and two alternative gH/gL complexes, gH/gL/gO (Trimer) and the gH/gL/UL128/UL130/UL131A (Pentamer) to enter into cells. The relative amounts of the Trimer and Pentamer vary among HCMV strains and contribute to differences in cell tropism. Although the viral ER resident protein UL148 has been show...

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Literature Corpus work
dbb5ddc2-2bd3-5995-a788-b42514e43ec2
DOI
10.1101/2020.11.18.387126
Open publication

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The human cytomegalovirus UL116 glycoprotein is a chaperone to control gH-based complexes levels on virionsDOI 10.1101/2020.11.18.387126
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