Article

Structural basis for NONO specific modification by the α-chloroacetamide compound <i>(R)</i> -SKBG-1

2025-06-12

Abstract excerpt

<h4>SUMMARY</h4> Among the many proteins involved in cancer progression an increasing number of RNA Binding Proteins (RBPs) are central to the function of a cell and tightly associated to genetic diseases as well as cancer appearance and progression. In a recent study, small molecule inhibitors have been identified as targeting NONO, a RBP known to be involved in mRNA splicing, DNA repair and membraneless organel...

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Literature Corpus work: db910054-cfd5-5431-93c0-dc00f7299fa5
DOI: 10.1101/2025.06.10.658868

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