Article

Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters

2024-07-22

Abstract excerpt

<h4>ABSTRACT</h4> Sterol transport proteins (STPs) play a pivotal role in cholesterol homeostasis and therefore are essential for healthy human physiology. Despite recent advances in dissecting functions of STPs in the human cell, there is still a significant knowledge gap regarding their specific biological functions and a lack of suitable selective probes for their study. Here, we profile fluorescent steroid-ba...

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Literature Corpus work: 62b860de-167a-5a57-82b5-a28c7773c92c
DOI: 10.1101/2024.07.22.604041

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