Article

Evaluation of Bayesian Linear Regression Models for Gene Set Prioritization in Complex Diseases

2024-02-26

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWAS) provide valuable insights into the genetic architecture of complex traits, yet interpreting their results remains challenging due to the polygenic nature of most traits. Gene set analysis offers a solution by aggregating genetic variants into biologically relevant pathways, enhancing the detection of coordinated effects across multiple genes. In this study,...

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Literature Corpus work: 2c2313e8-0f92-51f5-a30a-e0bfdd238523
DOI: 10.1101/2024.02.23.581718

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