Article

Selective role of the translin/trax RNase complex in hippocampal synaptic plasticity

2020-10-22

Abstract excerpt

<title>Abstract</title> <p>Activity-dependent local protein synthesis is critical for synapse-specific, persistent plasticity. Abnormalities in local protein synthesis have been implicated in psychiatric disorders. We have recently identified the translin/trax microRNA-degrading enzyme as a novel mediator of protein synthesis at activated synapses. Additionally, translin knockout (KO) mice, which lack translin/tr...

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Literature Corpus work: db6b64b7-9587-5bc5-90c1-bf73ebe91753
DOI: 10.21203/rs.3.rs-29690/v2

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