Article

Bacterial surface lipoproteins mediate epithelial microinvasion by <i>Streptococcus pneumoniae</i>

2023-10-19

Abstract excerpt

<h4>ABSTRACT</h4> Streptococcus pneumoniae , a common coloniser of the upper respiratory tract, invades nasopharyngeal epithelial cells without causing disease in healthy people. We hypothesised that surface expression of pneumococcal lipoproteins, recognised by the innate immune receptor TLR2, mediate epithelial microinvasion. Mutation of lgt in serotype 4 (TIGR4) and serotype 6B (BHN418) pneumococcal strains a...

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Literature Corpus work: cdd3d403-301e-5342-afb7-29bc54bdf13a
DOI: 10.1101/2023.10.18.562909

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