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Sex differences in diet-induced MASLD – are female mice naturally protected?

14 Mar 2025

Abstract excerpt

Males suffer more often from profibrotic changes in liver than females. The underlying mechanism for this sex difference in the prevalence and manifestation of Metabolic dysfunction-associated Steatotic Liver Disease (MASLD) is not yet completely known. We studied male and female mice that were induced to develop MASLD by consuming a “fast food” diet (FFD) and assessed metabolic phenotype as well as liver...

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Adipose Tissue and Metabolism
Diabetes and associated disorders
Pancreatic function and diabetes

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40162312
DOI: 10.3389/fendo.2025.1567573

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