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Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning

17 Jun 2020

Abstract excerpt

BACKGROUND & AIMS: Microsatellite instability (MSI) and mismatch-repair deficiency (dMMR) in colorectal tumors are used to select treatment for patients. Deep learning can detect MSI and dMMR in tumor samples on routine histology slides faster and less expensively than molecular assays. However, clinical application of this technology requires high performance and multisite validation, which have not yet been...

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PMID: 32562722
DOI: 10.1053/j.gastro.2020.06.021

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