Article

Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States

2024-09-25

Abstract excerpt

Influenza viruses continually evolve new antigenic variants, through mutations in epitopes of their major surface proteins, hemagglutinin (HA) and neuraminidase (NA). Antigenic drift potentiates the reinfection of previously infected individuals, but the contribution of this process to variability in annual epidemics is not well understood. Here, we link influenza A(H3N2) virus evolution to regional epidemic dynam...

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Literature Corpus work: daa2628f-1622-5583-8452-e96d133c2282
DOI: 10.7554/elife.91849.3

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