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The molecular determinants of antigenic drift in a novel avian influenza A (H9N2) variant virus

5 Feb 2022

Abstract excerpt

BACKGROUND: In early 2020, a novel H9N2 AIV immune escape variant emerged in South China and rapidly spread throughout mainland China. The effectiveness of the current H9N2 vaccine is being challenged by emerging immune escape strains. Assessing key amino acid substitutions that contribute to antigenic drift and immune escape in the HA gene of circulating strains is critical for understanding virus evolution and...

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PMID: 35123509
DOI: 10.1186/s12985-022-01755-9

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