Article

Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in <i>Caenorhabditis elegans</i>

2024-09-24

Abstract excerpt

RNA interference (RNAi) is widely used in life science research and is critical for diverse biological processes, such as germline development and antiviral defense. In Caenorhabditis elegans , RNA-dependent RNA polymerases, with redundant involvement of EGO-1 and RRF-1, facilitate small RNA amplification in germline exogenous RNAi (exo-RNAi). However, their coordination during the regulation of exo-RNAi processe...

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Literature Corpus work: 756df749-319c-502c-a190-049d04ae9c17
DOI: 10.1101/2024.09.24.614643

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