Article

Quantification of biases in predictions of protein-protein binding affinity changes upon mutations

2023-08-07

Abstract excerpt

Understanding the impact of mutations on protein-protein binding affinity is a key objective for a wide range of biotechnological applications and for shedding light on disease-causing mutations, which are often located at protein-protein interfaces. Over the past decade, many computational methods using physics-based and/or machine learning approaches have been developed to predict how protein binding affinity ch...

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Literature Corpus work: da8b6ae9-4875-5d88-925b-2e720cfb90d4
DOI: 10.1101/2023.08.04.551687

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