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Article

The impact of biological sex on alternative splicing

2018-12-10

Abstract excerpt

Over 95% of human genes undergo alternative splicing (AS) in a developmental, tissue-specific, or signal transduction-dependent manner. Here, we present a large-scale survey of sex-biased differential alternative splicing (DAS) across 7027 samples of 39 tissues from 532 individuals (351 males and 181 females) from the Genotype-Tissue Expression project. We detected a total of 1278 statistically significant DAS eve...

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Identifiers and source

Literature Corpus work
da7cf80f-dcdc-5e48-bd73-b507435f27c5
DOI
10.1101/490904
Open publication

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The impact of biological sex on alternative splicingDOI 10.1101/490904
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