Article

Muscle progenitor cells are required for the regenerative response and prevention of adipogenesis after limb ischemia

2020-02-26

Abstract excerpt

Peripheral artery disease (PAD) is nearly as common as coronary artery disease, but few effective treatments exist, and it is associated with significant morbidity and mortality. Although PAD studies have focused on the vascular response to ischemia, skeletal muscle cells play a critically important role in determining the phenotypic manifestation of PAD. Here, we demonstrate that genetic ablation of Pax7 + muscl...

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Literature Corpus work: da7c6203-3d8a-552a-a596-a42baa806ead
DOI: 10.1101/2020.02.24.963777

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