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Article

Icing after eccentric contraction-induced muscle damage perturbs the disappearance of necrotic muscle fibers and phenotypic dynamics of macrophages in mice.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 May 2021

Kawashima Masato, Kawanishi Noriaki, Tominaga Takaki, Suzuki Katsuhiko, Miyazaki Anna, Nagata Itsuki, Miyoshi Makoto, Miyakawa Motoi, Sakuraya Tohma, Sonomura Takahiro, Arakawa Takamitsu

Abstract excerpt

Icing is still one of the most common treatments to acute skeletal muscle damage in sports medicine. However, previous studies using rodents reported the detrimental effect of icing on muscle regeneration following injury. This study aimed to elucidate the critical factors governing the impairment of muscle regeneration by icing with a murine model of eccentric contraction-induced muscle damage by electrical...

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PMID: 33764172
DOI: 10.1152/japplphysiol.01069.2020

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