Article

Mesenchymal Stromal Cell Transplantation Ameliorates Fibrosis and Dysregulated microRNA Signature Associated with Ischaemic Skeletal Muscle Damage.

2024-02-27

Abstract excerpt

Peripheral arterial disease (PAD) is strongly associated with lower-extremity muscle wasting. Hallmark features of PAD associated skeletal muscle pathology include a loss of skeletal muscle mass, reduced strength and physical performance, as well as increased inflammation, fibrosis and adipocyte infiltration, among others. At a molecular level, skeletal muscle ischaemia has also been associated with gene and micro...

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Literature Corpus work: 2d2f88d2-8531-56e8-b3b9-faeca1e8e46e
DOI: 10.21203/rs.3.rs-3970387/v1

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