Article

Estimating Genetic Inheritance in Case-control Studies

2019-11-20

Abstract excerpt

Case-control genetic association study is an efficient tool to search for the deleterious genetic variants predispose to human complex diseases, where the additive mode of inheritance is commonly assumed. However, how the genetic variants influence the occurrence of a certain disease is impossible to know beforehand. We show numerically that the existing procedures using the Hardy-Weinberg equilibrium test to choo...

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Literature Corpus work: d9f290ed-727e-5bb7-913a-8aa5b49dc510
DOI: 10.1101/847269

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