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Article

Genetic model selection in two-phase analysis for case-control association studies.

Biostatistics (Oxford, England) - 1 Jul 2008

Zheng Gang, Ng Hon Keung Tony

Abstract excerpt

The Cochran-Armitage trend test (CATT) is well suited for testing association between a marker and a disease in case-control studies. When the underlying genetic model for the disease is known, the CATT optimal for the genetic model is used. For complex diseases, however, the genetic models of the true disease loci are unknown. In this situation, robust tests are preferable. We propose a two-phase analysis with...

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Identifiers

PMID: 18003629
DOI: 10.1093/biostatistics/kxm039
PMCID: PMC3294316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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