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Article

Fitting Proportional Odds Model to Case-Control data with Incorporating Hardy-Weinberg Equilibrium.

Scientific reports - 26 Nov 2015

Zhang Wei, Zhang Zehui, Li Xinmin, Li Qizhai

Abstract excerpt

Genetic association studies have been proved to be an efficient tool to reveal the aetiology of many human complex diseases and traits. When the phenotype is binary, the logistic regression model is commonly employed to evaluate the association strength of the genetic variants predispose to human diseases because the maximum likelihood estimator of the odds ratio based on case-control data is equivalent to that...

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PMID: 26607176
DOI: 10.1038/srep17286
PMCID: PMC4660314

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TRAF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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