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Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25-35

2022-09-06

Abstract excerpt

<title>Abstract</title> <p>Current evidence suggests that dexmedetomidine (Dex) can be used as an adjuvant to general anesthesia for the elderly with or without neurodegenerative diseases, such as Alzheimer's disease (AD), since it has perioperative analgesic properties and can prevent postoperative delirium. Dysfunction involving the autophagy-lysosomal pathway is thought to underlie the pathological mechanism o...

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Literature Corpus work
d9366dad-0682-5d3c-abcf-4129753c3ad7
DOI
10.21203/rs.3.rs-2008282/v1
Open publication

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