Back to search

Article

Effect of SNEDDS Loading Pentagamavunon-0 on Memory Impairment and Neurogenesis in Mice with Monosodium Glutamate-Induced Alzheimer’s Disease-Like Symptoms

2024-05-19

Abstract excerpt

<h4>ABSTRACT</h4> Pentagamavunon-0 (PGV-0), a curcumin analog, has antioxidant and HDAC2 inhibitory properties. It affects neurogenesis and cognitive function in Alzheimer’s disease (AD). Targeting neurogenesis is a strategy currently being developed for AD treatment. This study investigates the therapeutic potential of self-nanoemulsifying drug delivery systems loaded with PGV-0 (SNEDDS PGV-0) on spatial learnin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3733ebe2-3f4d-5b88-9855-9251f2952ffc
DOI
10.1101/2024.05.17.594779
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Effect of SNEDDS Loading Pentagamavunon-0 on Memory Impairment and Neurogenesis in Mice with Monosodium Glutamate-Induced Alzheimer’s Disease-Like SymptomsDOI 10.1101/2024.05.17.594779
Fe3O4@Polydopamine Nanoparticle-Loaded Human Umbilical Cord Mesenchymal Stem Cells Improve the Cognitive Function in Alzheimer's Disease Mice by Promoting Hippocampal NeurogenesisSemantic proximity
Withania somnifera (Ashwagandha) Improves Spatial Memory, Anxiety and Depressive-Like Behavior in the 5xFAD Mouse Model of Alzheimer’s DiseaseSemantic proximity
Human neural stem cell-derived extracellular vesicles remediate glioblastoma therapy-induced brain fogSemantic proximity
Fluvoxamine maleate ameliorates Alzheimer disease pathology by mitigating amyloid-beta load and neuroinflammation in 5XFAD miceSemantic proximity
Co-treatment With the Herbal Medicine SIP3 and Donepezil Improves Memory and Depression in the Mouse Model of Alzheimer’s DiseaseSemantic proximity
Tetrahydrohyperforin increases adult hippocampal neurogenesis in wild-type and APPswe/PS1ΔE9 mice.Semantic proximity
Molecular Mechanistic Insights of Pancharavinda Choornam in Cognitive Enhancement and Comorbidity Management in Neurodegenerative DiseaseSemantic proximity
Arginase Inhibition Supports Survival and Differentiation of Neuronal Precursors in Adult Alzheimer’s Disease MiceSemantic proximity
Dual role of Aβ42Os in adult hippocampal neurogenesis regulated by mGluR5 at different stages of Alzheimer's diseaseSemantic proximity
Enhancing Adult Neurogenesis Rescues Hippocampal Cognitive Functions in an Alzheimer’s Mouse ModelSemantic proximity
β-Cyclodextrin-Poly (β-Amino Ester) Nanoparticles Are a Generalizable Strategy for High Loading and Sustained Release of HDAC InhibitorsSemantic proximity
A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease.Semantic proximity
Select a neighboring publication to make it the new centre.