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The transcriptome and secreted factors of the intervertebral discs in STZ-HFD Type□2 diabetic male mice reveal extensive inflammation

2024-08-03

Abstract excerpt

The chronic inflammation observed during type 2 diabetes (T2D) is associated with spinal pathologies, including intervertebral disc (IVD) degeneration and chronic spine pain. Despite the presence of confounding factors, such as obesity, studies have shown that after adjusting for age, body mass index, and genetics (e.g. twins), patients with T2D suffer from disproportionately more IVD degeneration and/or back pain...

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Literature Corpus work
d92e4558-135a-57ff-95ad-d3156c367099
DOI
10.1101/2024.07.31.605332
Open publication

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The transcriptome and secreted factors of the intervertebral discs in STZ-HFD Type□2 diabetic male mice reveal extensive inflammationDOI 10.1101/2024.07.31.605332
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