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Complications in the spine associated with type 2 diabetes: The role of advanced glycation end-products

2 Mar 2021

Abstract excerpt

Type 2 diabetes mellitus (T2D) is an increasingly prevalent disease with numerous comorbidities including many in the spine. T2D is strongly linked with vertebral fractures, intervertebral disc (IVD) degeneration, and severe chronic spinal pain. Yet the causative mechanism for these musculoskeletal impairments remains unclear. The chronic hyperglycemic state in T2D promotes the formation of advanced glycation...

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PMID: 35992525
DOI: 10.1016/j.medntd.2021.100065

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