Article

Skip and bin: pervasive alternative splicing triggers degradation by nuclear RNA surveillance in fission yeast

2014-10-06

Abstract excerpt

Exon-skipping is considered a principal mechanism by which eukaryotic cells expand their transcriptome and proteome repertoires, creating different slice varaiants with distinct cellular functions. Here we analyze RNA-seq data from 116 transcriptomes in fission yeast ( Schizosaccharomyces pombe ), covering multiple physiological conditions as well as transcriptional and RNA processing mutants. We applied brute-fo...

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Literature Corpus work: 37fffb90-e260-545e-b774-299b79f72538
DOI: 10.1101/010033

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