Article

Evidence of a recombination rate valley in human regulatory domains

2016-04-15

Abstract excerpt

Human recombination rate varies greatly, but the forces shaping it remain incompletely understood. Here, we study the relationship between recombination rate and gene-regulatory domains defined by a gene and its linked control elements. We define these links using methylation quantitative trait loci (meQTLs), expression quantitative trait loci (eQTLs), chromatin conformation, and correlated activity across cell ty...

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Literature Corpus work: d8e08acb-34d6-546c-b462-874e1954f13c
DOI: 10.1101/048827

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