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Should deep-sequenced amplicons become the new gold-standard for analysing malaria drug clinical trials?

2021-03-23

Abstract excerpt

<h4>Background</h4> Regulatory clinical trials are required to ensure the continued supply and deployment of effective antimalarial drugs. Patient follow-up in such trials typically lasts several weeks as the drugs have long half-lives and new infections often occur during this period. “Molecular correction” is therefore used to distinguish drug failures from new infections. The current WHO-recommend method for m...

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Literature Corpus work
d8d3d12a-c12a-538e-876e-fc75333776db
DOI
10.1101/2021.03.23.436602
Open publication

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Should deep-sequenced amplicons become the new gold-standard for analysing malaria drug clinical trials?DOI 10.1101/2021.03.23.436602
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