Article
Molecular surveillance of Plasmodium falciparum drug-resistance markers in Vietnam using multiplex amplicon sequencing (2000-2016).
Scientific reports - 25 Aug 2023
Rovira-Vallbona Eduard, Kattenberg Johanna Helena, Hong Nguyen Van, Guetens Pieter, Imamura Hideo, Monsieurs Pieter, Chiheb Driss, Erhart Annette, Phuc Bui Quang, Xa Nguyen Xuan, Rosanas-Urgell Anna
Abstract excerpt
Emergence and spread of Plasmodium falciparum resistance to artemisinin-based combination therapies (ACT) is a major challenge for Greater Mekong Subregion countries in their goal to eliminate malaria by 2030. Tools to efficiently monitor drug resistance beyond resource-demanding therapeutic efficacy studies are necessary. A custom multiplex amplicon sequencing assay based on Illumina technology was designed to...
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