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Multiplexed nanopore amplicon sequencing to distinguish recrudescence from new infection in antimalarial drug trials

2024-09-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The assessment of antimalarial drug efficacy against Plasmodium falciparum requires PCR correction to distinguish recrudescence from new infections by comparing parasite genotypes before treatment and in recurrent infections. Nanopore sequencing offers a low-cost, portable, scalable, and rapid alternative to traditional methods, supporting the expansion and decentralization...

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Literature Corpus work
766c79f6-36d8-516e-909d-7fefb7e4de08
DOI
10.1101/2024.09.11.612449
Open publication

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