Article

Identifying progressive gene network perturbation from single-cell RNA-seq data

2018-04-07

Abstract excerpt

Identifying the gene regulatory networks that control development or disease is one of the most important problems in biology. Here, we introduce a computational approach, called PIPER ( P rogressIve network PER turbation), to identify the perturbed genes that drive differences in the gene regulatory network across different points in a biological progression. PIPER employs algorithms tailor-made for single cel...

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Literature Corpus work: b495328c-26cc-57ce-a87d-d77f53e82b37
DOI: 10.1101/297275

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