Article

Simvastatin Influences Selected Aspects of Duchenne Muscular Dystrophy Pathology in a Mouse Model

2021-01-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Duchenne muscular dystrophy (DMD) is an incurable disease, caused by the mutations in the <italic>DMD </italic>gene, encoding dystrophin, an actin-binding cytoskeletal protein. Lack of functional dystrophin results in muscle weakness, degeneration, and as an outcome cardiac and respiratory failure. As there is still no cure for affected individuals, the pharmaco...

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Literature Corpus work: d895357a-8de7-588c-88ad-99b7cb1d9f19
DOI: 10.21203/rs.3.rs-140320/v1

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