Article
Clinical characterization and molecular mechanisms of statin myopathy.
Expert review of cardiovascular therapy - 1 Aug 2008
Toth Peter P, Harper Charles R, Jacobson Terry A
Abstract excerpt
Myopathy has been reported in a small percentage of statin-treated patients for the past 30 years, but the etiologic mechanisms for inducing muscle injury have not yet been fully characterized. Statin-induced myopathy is now understood to be a heterogeneous condition that may be due to: mechanisms of the drug itself; interactions with other drugs; or genetic, metabolic and immunological vulnerabilities in...
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