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Article

Beneficial cilostazol therapeutic effects in mdx dystrophic skeletal muscle.

Clinical and experimental pharmacology & physiology - 1 Feb 2016

Hermes Túlio de Almeida, Macedo Aline Barbosa, Fogaça Aline Reis, Moraes Luis Henrique Rapucci, de Faria Felipe Meira, Kido Larissa Akemi, Cagnon Valéria Helena Alves, Minatel Elaine

Abstract excerpt

This study evaluated the possible protective effects of cilostazol against myonecrosis in dystrophic diaphragm muscle in vivo, focusing on oxidative stress, the inflammatory response and angiogenesis. Young mdx mice, the experimental animal for Duchenne muscular dystrophy, received cilostazol for 14 days. A second group of mdx mice and a control group of C57BL/10 mice received a saline solution. In the mdx mice,...

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Source

Identifiers

PMID: 26639107
DOI: 10.1111/1440-1681.12521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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