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High-dimensional deconstruction of pancreatic ductal adenocarcinoma identifies tumor microenvironmental communities associated with survival

2022-05-02

Abstract excerpt

<h4>ABSTRACT</h4> Bulk and single-cell analyses of the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME) have revealed a largely immunosuppressive milieu. Thus far, efforts to utilize insights from TME features to facilitate more effective therapeutics have largely failed. Here, we performed single-cell RNA sequencing (scRNA-seq) on a cohort of treatment-naive PDAC time-of-diagnosis endoscopic u...

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Literature Corpus work
024b6312-2dba-568d-b32e-3ae73108c0ff
DOI
10.1101/2022.04.29.22274376
Open publication

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