Article

Cardiolipin, and not monolysocardiolipin, preferentially binds to the interface of Complexes III and IV

2022-07-22

Abstract excerpt

The mitochondrial electron transport chain comprises a series of protein complexes embedded in the inner mitochondrial membrane that generate a proton motive force via oxidative phosphorylation, ultimately generating ATP. These protein complexes can oligomerize to form larger structures called supercomplexes. Cardiolipin (CL), a conical lipid, unique within eukaryotes to the inner mitochondrial membrane, has prove...

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Literature Corpus work: d878dcea-69b0-55f5-8cb1-c98f2209932c
DOI: 10.1101/2022.07.21.500943

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