Cell membranes sustain phospholipid imbalance via cholesterol asymmetry

Abstract excerpt

<h4>Summary</h4> Membranes are molecular interfaces that compartmentalize cells to control the flow of nutrients and information. These functions are facilitated by diverse collections of lipids, nearly all of which are distributed asymmetrically between the two bilayer leaflets. Most models of biomembrane structure and function often include the implicit assumption that these leaflets have similar abundances of...

Topics

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• Autophagy in Disease and Therapy
• Cellular transport and secretion
• Cholesterol and Lipid Metabolism
• Computational Drug Discovery Methods
• Endoplasmic Reticulum Stress and Disease
• Intracellular Space
• Lipid Droplets
• Phenotype

Identifiers and source

Literature Corpus work

e97a0e8e-c577-5e8e-aedb-2e83ba85e1f1

DOI

10.1101/2023.07.30.551157