Article

Identification and functional characterisation of different inner mitochondrial membrane supercomplexes

2020-01-01

Abstract excerpt

The inner mitochondria membrane (IMM) is densely packed with proteins necessary for mitochondrial activity, including oxidative phosphorylation (OXPHOS) complexes and transporters. Mitochondrial respiratory chain (MRC) complexes, which generate ATP by OXPHOS, associate in higher-order assemblies, known as supercomplexes (SC), that are structurally interdependent. Numerous patients carrying mutations in a single co...

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Literature Corpus work: 738bfb16-1dc9-55e3-863a-4f623136eaee
DOI: 10.17863/cam.63454

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