Article

Patterns of oncogene co-expression at single cell resolution in cancer influence survival

2020-10-23

Abstract excerpt

<h4>Background</h4> Cancers often overexpress multiple clinically relevant oncogenes. However, it is not known if multiple oncogenes within a cancer combine uniquely in specific cellular sub-populations to influence clinical outcome. We studied this phenomenon using the prognostically relevant oncogenes MYC, BCL2 and BCL6 in Diffuse Large B-Cell Lymphoma (DLBCL). <h4>Methods</h4> Quantitative multispectral imaging...

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Literature Corpus work: d861ebf5-b198-5804-8e48-d78d7f1532db
DOI: 10.1101/2020.10.20.20216101

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