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Intra-tumor heterogeneity of Diffuse Large B-cell Lymphoma involves the induction of diversified stroma-tumor interfaces

2020-05-31

Abstract excerpt

<h4>ABSTRACT</h4> Intra-tumor heterogeneity in lymphoid malignancies is articulated around several fundamentals, encompassing selection of genetic subclonal events and epigenetic regulation of transcriptional programs. Clonally-related neoplastic cell populations are unsteadily subjected to immune editing and metabolic adaptations within different tissue microenvironments. How tissue-intrinsic mesenchymal determi...

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Literature Corpus work
c085cbe1-211b-5bac-97d6-59b51be5af90
DOI
10.1101/2020.05.30.124859
Open publication

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Intra-tumor heterogeneity of Diffuse Large B-cell Lymphoma involves the induction of diversified stroma-tumor interfacesDOI 10.1101/2020.05.30.124859
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