Back to search

Article

Genetics of 38 blood and urine biomarkers in the UK Biobank

2019-06-05

Abstract excerpt

Clinical laboratory tests are a critical component of the continuum of care and provide a means for rapid diagnosis and monitoring of chronic disease. In this study, we systematically evaluated the genetic basis of 38 blood and urine laboratory tests measured in 358,072 participants in the UK Biobank and identified 1,857 independent loci associated with at least one laboratory test, including 488 large-effect prot...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d8326ca3-8773-5034-ab50-0814244d0b27
DOI
10.1101/660506
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetics of 38 blood and urine biomarkers in the UK BiobankDOI 10.1101/660506
Genetics of 35 blood and urine biomarkers in the UK Biobank.Semantic proximity
Genetic analyses in UK Biobank identifies 78 novel loci associated with urinary biomarkers providing new insights into the biology of kidney function and chronic diseaseSemantic proximity
Analyses of Biomarker Traits in Diverse UK Biobank Participants Identify Associations Missed by European-centric Analysis StrategiesSemantic proximity
Effects of protein-coding variants on blood metabolite measurements and clinical biomarkers in the UK Biobank.Semantic proximity
Phenome-wide study on alcohol consumption provides genetic evidence for a causal association with multiple diseases and biomarkers.Semantic proximity
Cardiovascular-kidney-metabolic health, genetic susceptibility, and incident cancer risk: a prospective UK biobank cohort and machine learning study.Semantic proximity
Analysis of biomarkers in the Human Phenotype Project using disease models from UK Biobank.Semantic proximity
Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex diseaseSemantic proximity
Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies.Semantic proximity
Analysis of whole genome sequencing and plasma metabolomics unveil genetic determinants and clinical implications for human health.Semantic proximity
Assessing the contribution of rare-to-common protein-coding variants to circulating metabolic biomarker levels via 412,394 UK Biobank exome sequencesSemantic proximity
Machine Learning Prediction of Biomarkers from SNPs and of Disease Risk from Biomarkers in the UK BiobankSemantic proximity
Select a neighboring publication to make it the new centre.